Microcirculation in the myocardium.

The myocardial microcirculation: A key target for salvaging ischemic myocardium?

Clinical management of patients with acute myocardial infarction for the most part involves re-opening of an infarct-related coronary vessel by the use of clot-busting pharmacologic treatment or percutaneous coronary interventions. While blood flow in the epicardial coronary vessel is restored downstream, effects remain largely unexplored; progressive injury at the microvessel level has signifi...

Tissue ACE inhibition improves microcirculation in remote myocardium after coronary stenosis: MR imaging study in rats.

ACE inhibition has been shown to improve left ventricular (LV) and myocardial blood flow. Previous data regarding changes in capillary density and angiogenesis during ACE inhibition are controversial. The aim of the following study was to determine myocardial microcirculation and heart function in the rat after coronary stenosis using non invasive MR imaging techniques. MR spin labeling and cin...

The microcirculation in shock.

It is right that attention should be directed early in this symposium to the microcirculation in shock for it is at this level of the circulation that we must look for an explanation of this complex and sometimes irreversible clinical condition. The word 'shock' is convenient and firmly established in medical usage but gives no indication of the multifactorial nature of a process probably best ...

Renaissance in the microcirculation.

The microcirculation in atherogenesis.

The term ‘atherosclerosis’ is generally employed for a disease process characterized by the formation of atheromas (fibrofatty intimal plaques) resulting in progressive hardening of the arterial wall, loss of vascular elasticity, and luminal compromise. Different segments of the vascular tree vary in their susceptibility to develop atherosclerotic lesions: atheromas have been described characte...